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Trochlear nerve course

Which cranial nerve is the only one to emerge from the dorsal surface of the brainstem and to cross to the opposite side before reaching its target?

Explanation

Key fact
The trochlear nerve is the only cranial nerve that leaves the brainstem dorsally and decussates. Both facts follow from where its nucleus sits.

The trochlear nerve. It emerges behind the midbrain, wraps round it, and supplies the superior oblique of the *opposite* side.

Why

Its nucleus lies in the midbrain, but the fibres run backwards and cross.

They emerge below the inferior colliculus, on the dorsal surface.

Each nerve therefore supplies the superior oblique of the other side.

That long, exposed course makes it the most easily injured in head trauma.

The trochlear nerve leaves the brainstem from behind

A side view of the brainstem showing the trochlear nucleus in the midbrain, fibres running backwards and crossing in the superior medullary velum, and the nerve emerging dorsally below the inferior colliculus to curve round to the opposite superior oblique

Why not the others

Remember
Fourth is the odd one: out the back, and over the other side.

Go deeper

A trochlear palsy gives vertical diplopia that is worst on looking down and in, so the patient tilts the head away from the affected side - the Bielschowsky test.

Because the nerve is thin and travels far, it is the commonest cranial nerve palsy after closed head injury.

The diabetic third nerve palsy in the seed spares the pupil, because the ischaemia hits the central fibres and leaves the superficial parasympathetics intact.

Snell's Clinical Anatomy by Regions, 11th ed. (Wolters Kluwer, 2024); Gray's Anatomy for Students, 5th ed. (Elsevier, 2023).

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