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Infantile hypertrophic pyloric stenosis

A 5-week-old firstborn boy has three days of forceful non-bilious vomiting immediately after feeds and is now losing weight. He remains hungry. When is the olive-shaped pyloric mass most reliably felt, and what electrolyte picture is expected?

Explanation

Key fact
Feed the baby to feel the olive. Sucking relaxes the abdominal wall, and vomiting gastric acid produces an alkalosis, not an acidosis.

During a test feed, with hypochloraemic hypokalaemic metabolic alkalosis. Both halves follow from the mechanism.

Why

A crying infant tenses the abdominal wall and hides the mass.

Sucking on a feed relaxes it, and the pylorus can be rolled under the fingers.

The vomit is gastric content, so hydrogen and chloride are lost.

The kidney then retains sodium in exchange for potassium and hydrogen.

That paradoxically acid urine with alkalotic blood is characteristic.

The test feed and the metabolic consequence

Two linked panels: an infant feeding from a bottle with an examiner's hand palpating an olive-shaped mass in the right upper quadrant lateral to the rectus, and a flow diagram of loss of hydrogen and chloride in vomit leading to hypochloraemic hypokalaemic metabolic alkalosis with paradoxical aciduria

Why not the others

Remember
Feed to feel it; alkalosis, not acidosis.

Go deeper

This is a medical emergency before it is a surgical one: the alkalosis and dehydration must be corrected before anaesthesia, or apnoea may follow.

Ultrasound has largely replaced the test feed, with a muscle thickness above about 3 to 4 mm and a channel length above 15 to 17 mm being diagnostic.

The operation is a Ramstedt pyloromyotomy, splitting the muscle without opening the mucosa; feeding usually restarts within hours.

Bailey & Love's Short Practice of Surgery, 28th ed. (CRC Press, 2023); Ghai Essential Pediatrics, 10th ed. (CBS Publishers, 2025).

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