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Pharmacology questions for NEET PG
747 Pharmacology questions in the Recallab bank, each with a verified answer, every option explained and a reference to a current edition. 6 of them are published in full — the rest are in the app.
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- Which of the following is a drug containing two sulfhydryl groups in a molecule?
- In low doses, aspirin inhibits which of the following mediators?
- Which of the following statement is true regarding inverse agonists?
- Which of the following best describes the mechanism of action of benzodiazepines?
- A 64-year-old man has taken amiodarone for ten months for recurrent ventricular tachycardia after a myocardial infarction. He now reports fatigue, a 4 kg weight gain and cold intolerance. TSH is 14…
- A patient with hyperkalaemia is given nebulised salbutamol and the serum potassium falls within 30 minutes without any change in urine output. Which mechanism accounts for this?
- A 22-year-old woman is brought in three hours after taking about 60 aspirin tablets. She has tinnitus, vomiting and is breathing deeply at 30 per minute. Arterial blood gas shows pH 7.44, PaCO2 22…
- A 34-year-old woman in thyroid storm has a heart rate of 150 and a temperature of 39.5 degrees Celsius. She has no asthma. Beyond controlling the heart rate, which additional property makes…
- A 48-year-old man with hypertension has had three episodes of calcium oxalate stones and a 24-hour urine calcium of 380 mg. He is started on hydrochlorothiazide. By what mechanism does this reduce…
- Sacubitril is combined with valsartan for heart failure with reduced ejection fraction. What is the pharmacological effect of the sacubitril component?
- A 63-year-old woman, eight years postmenopausal, has a hip T-score of -2.8 and no fragility fracture. Serum calcium, vitamin D and renal function are normal and she has no oesophageal disease. What…
- By what mechanism does colchicine relieve an acute attack of gout?
- A 48-year-old man with chronic obstructive pulmonary disease has been stable on oral theophylline for two years. Ten days after starting an antibiotic for a chest infection he develops nausea…
- A 71-year-old man on warfarin for atrial fibrillation is admitted with a large intracerebral haemorrhage. His INR is 6.2. Which is the most appropriate agent for immediate reversal?
- Which anticoagulant acts by direct inhibition of factor Xa and is given orally?
- A 74-year-old woman on digoxin for heart failure is admitted vomiting, confused and seeing yellow-green halos around lights. Her heart rate is 38 with regularised atrial fibrillation, potassium is…
- A 27-year-old woman starts standard four-drug antitubercular treatment. She takes a combined oral contraceptive pill. Six weeks later she is found to be pregnant. What is the mechanism?
- Minutes after an intramuscular injection a 30-year-old woman develops widespread urticaria, stridor, wheeze and a blood pressure of 74/40 mmHg. Which drug, dose, concentration and route should be…
- A man on metformin is admitted with vomiting, dehydration and acute kidney injury. Arterial pH is 7.10 with a high anion gap and a lactate of 9 mmol/L. Which mechanism links the drug to the acidosis…
- Six hours after a first dose of an antiemetic for chemotherapy-induced vomiting, a 19-year-old develops involuntary neck twisting, jaw spasm and forced upward deviation of the eyes. He is fully alert…
- Nitrogen-containing bisphosphonates such as alendronate reduce fracture risk in postmenopausal osteoporosis. Which enzyme do they inhibit, and in which cell?
- A patient on high-dose methotrexate develops painful oral ulceration and neutropenia. Folinic acid is given as rescue. Which nucleotide has fallen, and why does folinic acid work when folic acid…
- A man with HIV and chronic hepatitis B co-infection is starting antiretroviral therapy. Why must the regimen include tenofovir, and what happens if drugs active against hepatitis B are later stopped…
- A man with treatment-resistant schizophrenia is switched from haloperidol to a new agent. He develops drooling, weight gain and a rising fasting glucose, but his tremor and rigidity improve. Which…
- Three weeks after starting haloperidol a man develops a symmetrical resting tremor, rigidity and bradykinesia. The psychosis is well controlled. Which drug should be added, and why is levodopa NOT…